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Remedy to be Reading Glasses Free?

Remedy to be Reading Glasses Free

A thin ring inserted into the eye could soon offer a reading glasses free remedy for presbyopia the blurriness in near vision experienced by many people older than the age of 40, according to a study released by the American Academy of Ophthalmology.

A corneal inlay device currently undergoing clinical review in the United States improved near vision well enough for 80 percent of the participating patients to read a newspaper without disturbing far distance vision needed for daily activities like driving.

Presbyopia affects more than 1 billion people worldwide. As people age, the cornea becomes less flexible and bends in such a way that it becomes difficult to see up close. Although the most common remedy is wearing reading glasses, a host of new corneal inlay products are in development to treat the condition, with three types currently under review by the US Food and Drug Administration (FDA).

The theoretical advantage of using corneal inlays rather than wearing reading glasses is that corneal inlays prevent the need for constantly putting on and taking off glasses, depending on whether the person needs to see near or far.

One of the devices is the KAMRA inlay, a thin, flexible, doughnut-shaped ring that measures 3.8 millimeters in diameter, with a 1.6 millimeter hole in the middle. When dropped into a small pocket in the cornea covering the front of the eye, the device acts like a camera aperture, adjusting the depth of field so that the viewer can see near and far. The procedure to insert the implant is relatively quick, lasting about 10 minutes, and requires only topical anesthesia.

To test the inlay's efficacy, clinicians conducted a prospective non-randomized study of 507 patients with presbyopia who were not nearsighted, between 45 and 60 years of age, across the United States, Europe, and Asia. The researchers implanted the ring in the patients and followed up with them over the course of three years.

In 83 percent of eyes with the implant, the KAMRA corneal inlay allowed presbyopic patients to see with 20/40 vision or better during the three years. This is considered the standard for being able to read a newspaper or drive a vehicle without corrective lenses. On average, patients gained 2.9 lines on a reading chart. The researchers report that the results remained steady across a three-year period.

Complications from corneal inlays in general have included haziness that is treatable with steroids; however, improvements in inlay design have made the effect less common. If necessary, inlays can be removed, making it a reversible treatment, unlike other procedures such as LASIK for presbyopia.

"This is a solution that truly delivers near vision that transitions smoothly to far distance vision," said John Vukich, MD, author of the poster and a clinical adjunct professor in ophthalmology and vision sciences at the University of Wisconsin, Madison. "Corneal inlays represent a great opportunity to improve vision with a safety net of removability."

The device is sold in regions including Asia, Europe, and South America, but is not yet approved by the FDA for use in the United States. There are two other types of corneal inlays, Raindrop Near Vision Inlay and Presbia Flexivue Microlens, also in development for the US market.

Source: American Academy of Ophthalmology, aao.org

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